Bow your head, pray to God. Ask for mercy.
Seriously, if you have more talent than your only option is to outscore him. Also if his guards sick, you could try to ramp up the OD and force turnovers.
SB can help defend against interior offense but SB levels are too low across the board. You need a guy with a high calibrr of BOTH ID and SB to defend the monster LI. No teams have this or can afford to have this.