What is your take on training U21 players that have HOF potential compared to Superstar potential? Do you have the players train the same or do you force more primary training on the superstar guy to benefit the U21 team more?
That depends on a few things. To start, for HOFer's, it depends on what the managers want to do. If the manager clearly states that they do not want to train for NT, then I would have them focus on U21. Regardless of position, it is difficult to get a player on U21 if you are strictly training for NT. For SS's it gets tricky toward the end of the season for bigs because they will begin to cap. A little bit of secondaries would be nice for them.
A lot of U21 teams have donkey bigs with high primaries and 1’s everywhere else. How do you feel about this? How might you exploit that?
Was going to mention this in the above answer, but I personally am a big fan of having versatile players(bigs especially). I think donkey bigs a very vulnerable and easy to expose, although I do not want to voice how I would do that on this thread(gotta keep some things secret

).
What is your take on outside offenses? What skills do you look at for outside offenses compared to inside offenses? What would be your ideal outside offense lineup?
Outside offenses are underrated. Everyone wants to go inside nowadays meanwhile there is an entire other set of tactics completely usable. Skills needed are obviously the shooting ones, but passing would also still remain highly important in both. The ideal lineup is hard to state from a generalist standpoint, but I would want good outside shooters at the 1-3, and an all around scorer at the 4. All of which can all ideally pass and defend well.
In your own opinion, how do you think the Game Engine works in regards to tactics? Specifically, I want to hear how you think a LI works compared to a RnG? For example, does the GE value passing as much as DR? Is JR useful in LI? Does IS matter in a RnG? What do you think?
Ahhh the GE. That thing does what it wants. From what I experienced, it definitely values some skills over others. It likes to "go by definition" if you will. I think IS is important across the board in an LI, PA important in motion, to name a few. The GE looks for these things in order to have a high offensive flow.
Pick 2 of the three guards for your team:
14/14/13/12/12/7-6/5/4/3
12/7/13/12/12/9/11/5/4/3
15/6/13/13/13/13-2/5/4/3
Players 1 and 2.
Player 1:
PA till 9
OD till 15
1v1G till 15(or 16)JS, 14 DR/HD
OD to 16
If any time left, JS for the rest
Player 2:
PA till 12
OD till 15
1v1G till 14 HD/DR
OD/PA for the rest